Cochrane Vascular Register

The Cochrane Vascular Group Information Specialist maintains a specialised register of vascular trials, and every month the following sources are searched :

MEDLINE (via Ovid SP)
Embase (via Ovid SP)
CINAHL (EBSCO)
ClinicalTrials.gov
WHO’s ICTRP meta-registry
CENTRAL (via the Cochrane Library)

The searches that are run in the sources listed above are sensitive searches, which means that they retrieve a very high proportion of references which are relevant to the work of the group. This sensitivity comes at a cost because it means that the searches also retrieve a fairly high proportion of irrelevant records. The search results are therefore screened, so that records which are not relevant to the scope of the group or records that are not randomised or quasi-randomised trials, are identified and discarded. We then add relevant records to the register and submit them for publication in CENTRAL. The following searches are run:

MEDLINE (via Ovid SP)

1. exp Aortic Aneurysm/
2. exp Arterial Occlusive Diseases/
3. Arteriosclerosis Obliterans/
4. Iliac Aneurysm/
5. Intermittent Claudication/
6. exp Peripheral Vascular Diseases/
7. exp Pulmonary Embolism/
8. exp Telangiectasis/
9. Thromboembolism/
10. exp Thrombophlebitis/
11. Upper Extremity Deep Vein Thrombosis/
12. exp Varicose Veins/
13. Vascular Patency/
14. exp Venous Insufficiency/
15. Venous Thromboembolism/
16. Venous Thrombosis/
17. Aorta/su or Axillary Artery/su or Axillary Vein/su or Brachial Artery/su or Aorta, Thoracic/su or Femoral Artery/su or Femoral Vein/su or Iliac Artery/su or Iliac Vein/su or Popliteal Artery/su or Popliteal Vein/su or Radial Artery/su or Saphenous Vein/su or Subclavian Artery/su or Subclavian Vein/su or Tibial Arteries/su or Ulnar Artery/su
18. ((varico* or reticular or thread or spider) adj2 (vein* or venous)). ti,ab.
19. ((vein* or enous*) adj (insufficien* or incomp*)). ti,ab.
20. AAA.ti,ab.
21. abdominal aneurysm*. ti,ab.
22. abdominal aortic aneurysm. ti,ab.
23. ankle brachial index. ti,ab.
24. arterial stenosis. ti,ab.
25. chronic limb ischaemia. ti,ab.
26. chronic limb ischemia. ti,ab.
27. claudication. ti,ab.
28. critical limb ischemia. ti,ab.
29. critical limb ischaemia.ti,ab.
30. deep vein thrombosis. ti,ab.
31. DVT. ti,ab.
32. dysvascular*. ti,ab.
33. endovascular aneurysm repair. ti,ab.
34. endovascular stent*. ti,ab.
35. EVAR. ti,ab.
36. lower limb ischemia. ti,ab.
37. lower limb ischaemia.ti,ab.
38. lung emb*. ti,ab.
39. microvarice*. ti,ab.
40. PAOD. ti,ab.
41. (peripheral* adj3 disease*). ti,ab.
42. periphlebitis. ti,ab.
43. phlebitis. ti,ab.
44. post thrombotic syndrome. ti,ab.
45. postthrombotic syndrome. ti,ab.
46. post-thrombotic syndrome. ti,ab.
47. pulmonary emboli*. ti,ab.
48. PVD. ti,ab.
49. telangiectasis. ti,ab.
50. TEVAR. ti,ab.
51. thoracic endovascular aortic repair. ti,ab.
52. thrombophlebitis. ti,ab.
53. thrombosis. ti,ab.
54. thrombus in the deep veins. ti,ab.
55. venous catheterization. ti,ab.
56. venous catheterisation. ti,ab.
57. venous circulation. ti,ab.
58. venous thromboemboli*. ti,ab.
59. venous thrombosis. ti,ab.
60. VTE. ti,ab.
61. (("abdominal aorta" or "axillary arter*" or "axillary vein*" or "basilic vein*" or "brachial arter*" or "cephalic vein*" or "cubital vein*" or "descending aorta" or "dorsal pedis arter*" or "dorsal venous arter*" or "dorsalis arter*" or "femoral arter*" or "femoral vein*" or "iliac arter*" or "iliac vein*" or "perforating vein*" or "peroneal arter*" or "plantar arter*" or "popliteal arter*" or "popliteal vein*" or "radial arter*" or "saphenous vein*" or "subclavian arter*" or "subclavian vein*" or "tibial arter*" or "tibial vein*" or "ulnar arter*") adj (anastomos* or aneurysm* or angioplast* or bypass or construct* or dilation or dissect* or evulsion or graft or lesion* or obstruct* or occlus* or pseudo or recanal* or reconstruct* or re-construct* or reocclu* or re-occlus* or revascular* or steno* or tent* or strip* or surg* or tear or transect* or re-stenos* or endovascular surg*)). ti,ab.
62. or/1-61
63. ATHEROSCLEROSIS/
64. ARTERIOSCLEROSIS/
65. arteriosclero*. ti,ab.
66. atherosclero*. ti,ab.
67. atherothrombo*. ti,ab.
68. (blood adj3 (clot* or stasis)). ti,ab.
69. or/63-68
70. ("abdominal aorta" or "axillary arter*" or "axillary vein*" or "basilic vein*" or "brachial arter*" or "cephalic vein*" or "cubital vein*" or "descending aorta" or "dorsal pedis arter*" or "dorsal venous arter*" or "dorsalis arter*" or "femoral arter*" or "femoral vein*" or "iliac arter*" or "iliac vein*" or "perforating vein*" or "peroneal arter*" or "plantar arter*" or "popliteal arter*" or "popliteal vein*" or "radial arter*" or "saphenous vein*" or "subclavian arter*" or "subclavian vein*" or "tibial arter*" or "tibial vein*" or "ulnar arter*" or arm or arms or leg or legs or limb or limbs or peripher* or hand or hands or foot or feet). ti,ab.
71. 69 and 70
72. 62 or 71
73. randomized controlled trial. pt.
74. controlled clinical trial. pt.
75. randomized. ab.
76. placebo. ab.
77. drug therapy. fs.
78. randomly. ab.
79. trial. ab.
80. groups. ab.
81. or/73-80
82. exp animals/ not humans. sh.
83. 81 not 82
84. 72 and 83

Embase (via Ovid SP)

1. AMPUTATION/ and LEG/
2. dissecting aneurysm/
3. false aneurysm/
4. peripheral occlusive artery disease/
5. exp aneurysm rupture/
6. exp aortic aneurysm/
7. exp embolism/
8. exp peripheral vascular disease/
9. exp telangiectasia/
10. exp varicosis/
11. VENOUS INSUFFICIENCY/
12. exp iliac artery aneurysm/
13. intermittent claudication/
14. lung embolism/
15. thromboembolism/
16. thrombophlebitis/
17. upper extremity deep vein thrombosis/
18. vascular patency/
19. venous thromboembolism/
20. vein thrombosis/
21. ((aort* or thorac* or iliac) adj3 (transect* or tear or dilation or aneurysm* or pseudo* or dissect*)).ti,ab.
22. ((angioplast* or stent*) adj3 (femoro* or tibial or tibio* or infra* or iliac or aortoiliac or poplit*)).ti,ab.
23. ((arter* or vascu* or vein* or venous) adj3 (obstruct* or occlus* or lesion* or steno* or re-stenos* or restenos* or isch?em* or atherosclero*)).ti,ab.
24. ((endovascular adj3 surg*) and (femoro* or tibial or tibio* or infra* or iliac or aortoiliac or poplit*)).ti,ab.
25. ((femoro* or tibial or tibio* or infra* or iliac or aortoiliac or poplit*) adj3 (bypass or graft or anastomos* or surg* or strip* or evulsion or recanal* or revascular* or reconstruct* or re-construct* or construct* or occlu* or re-occlu* or reocclu*)).ti,ab.
26. ((leg* or limb*) adj3 (obstruct* or occlus* or lesion* or steno* or isch?em* or atherosclero*)).ti,ab.
27. ((post-phlebitic or postphlebitic or postthrombotic or post-thrombo*) adj3 (syndrome or dis*)).ti,ab.
28. ((pulmonary or lung) adj3 embol*).ti,ab.
29. ((varico* or reticular or thread or spider) adj3 (vein* or venous)).ti,ab.
30. ((vein* or venous*) adj3 (insufficien* or incomp* or stasis)).ti,ab.
31. (aort* adj (balloon* or bulg*)).ti,ab.
32. (EMBOLECTOMY/ or exp ANGIOPLASTY/ or RADIOGRAPHY, INTERVENTIONAL/ or LIMB SALVAGE/ or THROMBECTOMY/) and (femoro* or tibial or tibio* or infra* or iliac or aortoiliac or poplit*).ti,ab.
33. (FEMORAL ARTERY/ or POPLITEAL ARTERY/ or ILIAC ARTERY/ or TIBIAL ARTERIES/ or femoro*.ti,ab. or tibial.ti,ab. or tibio*.ti,ab. or infra*.ti,ab. or iliac.ti,ab. or aortoiliac.ti,ab. or poplit*.ti,ab.) and (obstruct* or occlus* or lesion* or steno* or isch?em* or atherosclero*).ti,ab.
34. (peripher* adj3 (occlu* or arteri* or vascular or diseas*)).ti,ab.
35. AORTA/su or AXILLARY ARTERY/su or AXILLARY VEIN/su or BRACHIAL ARTERY/su or AORTA, THORACIC/su or FEMORAL ARTERY/su or FEMORAL VEIN/su or ILIAC ARTERY/su or ILIAC VEIN/su or POPLITEAL ARTERY/su or POPLITEAL VEIN/su or RADIAL ARTERY/su or SAPHENOUS VEIN/su or SUBCLAVIAN ARTERY/su or SUBCLAVIAN VEIN/su or TIBIAL ARTERIES/su or ULNAR ARTERY/su
36. claudicat*.ti,ab.
37. dvt.ti,ab.
38. dysvascular*.ti,ab.
39. microthrombus.ti,ab.
40. microvarice*.ti,ab.
41. PAOD.ti,ab.
42. periphlebitis.ti,ab.
43. phlebitis.ti,ab.
44. PVD.ti,ab.
45. telangiectasis.ti,ab.
46. thromboemboli*.ti,ab.
47. thrombotic.ti,ab.
48. thrombus.ti,ab.
49. or/1-48
50. ATHEROSCLEROSIS/
51. ARTERIOSCLEROSIS/
52. (arteriosclero* or atherosclero* or atherothrombo*).ti,ab.
53. (blood adj3 (clot* or stasis)).ti,ab.
54. or/50-53
55. ("abdominal aorta" or "arch of aorta" or "ascending aorta" or "axillary arter*" or "axillary vein*" or "basilic vein*" or "brachial arter*" or "Brachial arter*" or "brachiocephalic trunk" or "cephalic vein*" or "common femoral arter*" or "common Iliac artery" or "cubital vein*" or "deep femoral arter*" or "descending aorta" or "dorsal pedis arter*" or "dorsal venous arter*" or "dorsalis arter*" or "femoral arter*" or "femoral superficial arter*" or "femoral vein*" or "fibular artery" or "hypogastric artery" or "iliac arter*" or "iliac vein*" or "inferior vena cava" or "infrarenal aorta" or "innominate artery" or "internal Iliac artery" or "internal Iliac artery" or "internal iliac artery" or "perforating vein*" or "peroneal arter*" or "plantar arter*" or "popliteal arter*" or "popliteal vein" or "profunda femoris arter*" or "radial arter*" or "saphenous vein*" or "subclavian arter*" or "subclavian vein*" or "superior vena cava" or "thoracic aorta" or "tibial arte*" or "tibial vein*" or "ulnar arter*" or arm or arms or leg or legs or limb or limbs or peripher* or hand or hands or foot or feet).ti,ab.
56. 54 and 55
57. 49 or 56
58. randomized controlled trial/
59. controlled clinical trial/
60. random$.ti,ab.
61. randomization/
62. intermethod comparison/
63. placebo.ti,ab.
64. (compare or compared or comparison).ti.
65. ((evaluated or evaluate or evaluating or assessed or assess) and (compare or compared or comparing or comparison)).ab.
66. (open adj label).ti,ab.
67. ((double or single or doubly or singly) adj (blind or blinded or blindly)).ti,ab.
68. double blind procedure/
69. parallel group$1.ti,ab.
70. (crossover or cross over).ti,ab.
71. ((assign$ or match or matched or allocation) adj5 (alternate or group$1 or intervention$1 or patient$1 or subject$1 or participant$1)).ti,ab.
72. (assigned or allocated).ti,ab.
73. (controlled adj7 (study or design or trial)).ti,ab.
74. (volunteer or volunteers).ti,ab.
75. trial.ti.
76. or/58-75
77. 57 and 76

CINAHL (EBSCO)

S103. S87 AND S102
S102. S88 OR S89 OR S90 OR S91 OR S92 OR S93 OR S94 OR S95 OR S96 OR S97 OR S98 OR S99 OR S100 OR S101
S101. MH "Random Assignment"
S100. MH "Triple-Blind Studies"
S99. MH "Double-Blind Studies"
S98. MH "Single-Blind Studies"
S97. MH "Crossover Design"
S96. MH "Factorial Design"
S95. MH "Placebos"
S94. MH "Clinical Trials"
S93. TX "multi-centre study" OR "multi-center study" OR "multicentre study" OR "multicenter study" OR "multi-site study"
S92. TX crossover OR "cross-over"
S91. AB placebo*
S90. TX random*
S89. TX trial*
S88. TX "latin square"
S87. S77 OR S86
S86. S84 AND S85
S85. TX "abdominal aorta" or "axillary arter*" or "axillary vein*" or "basilic vein*" or "brachial arter*" or "cephalic vein*" or "cubital vein*" or "descending aorta" or "dorsal pedis arter*" or "dorsal venous arter*" or "dorsalis arter*" or "femoral arter*" or "femoral vein*" or "iliac arter*" or "iliac vein*" or "perforating vein*" or "peroneal arter*" or "plantar arter*" or "popliteal arter*" or "popliteal vein*" or "radial arter*" or "saphenous vein*" or "subclavian arter*" or "subclavian vein*" or "tibial arter*" or "tibial vein*" or "ulnar arter*" or arm or arms or leg or legs or limb or limbs or peripher* or hand or hands or foot or feet
S84. S78 OR S79 OR S80 OR S81 OR S82 OR S83
S83. TX (blood n3 clot* or stasis)
S82. TX atherothrombo*
S81. TX atherosclero*
S80. TX arteriosclero*
S79. (MH "Arteriosclerosis")
S78. (MH "Atherosclerosis")
S77. S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 OR S46 OR S47 OR S48 OR S49 OR S50 OR S51 OR S52 OR S53 OR S54 OR S55 OR S56 OR S57 OR S58 OR S59 OR S60 OR S61 OR S62 OR S63 OR S64 OR S65 OR S66 OR S67 OR S68 OR S69 OR S70 OR S71 OR S72 OR S73 OR S74 OR S75 OR S76
S76. TX (("abdominal aorta" or "axillary arter*" or "axillary vein*" or "basilic vein*" or "brachial arter*" or "cephalic vein*" or "cubital vein*" or "descending aorta" or "dorsal pedis arter*" or "dorsal venous arter*" or "dorsalis arter*" or "femoral arter*" or "femoral vein*" or "iliac arter*" or "iliac vein*" or "perforating vein*" or "peroneal arter*" or "plantar arter*" or "popliteal arter*" or "popliteal vein*" or "radial arter*" or "saphenous vein*" or "subclavian arter*" or "subclavian vein*" or "tibial arter*" or "tibial vein*" or "ulnar arter*") N2 (anastomos* or aneurysm* or angioplast* or bypass or construct* or dilation or dissect* or evulsion or graft or lesion* or obstruct* or occlus* or pseudo or recanal* or reconstruct* or re-construct* or reocclu* or re-occlus* or revascular* or steno* or tent* or strip* or surg* or tear or transect* or re-stenos* or endovascular surg*))
S75. TX VTE
S74. TX venous thrombosis
S73. TX venous thromboemboli*
S72. TX venous circulation
S71. TX venous catheterisation
S70. TX venous catheterization
S69. TX thrombus in the deep veins
S68. TX thrombosis
S67. TX thrombophlebitis
S66. TX thoracic endovascular aortic repair
S65. TX TEVAR
S64. TX telangiectasis
S63. TX PVD
S62. TX pulmonary emboli*
S61. TX pulmonary emboli*
S60. TX post-thrombotic syndrome
S59. TX postthrombotic syndrome
S58. TX post thrombotic syndrome
S57. TX phlebitis
S56. TX periphlebitis
S55. TX peripheral* n3 disease*
S54. TX PAOD
S53. TX microvarice*
S52. TX lung emb*
S51. TX lower limb ischemia
50. TX lower limb ischaemia
S49. TX EVAR
S48. TX endovascular stent*
S47. TX endovascular aneurysm repair
S46. TX dysvascular*
S45. TX DVT
S44. TX deep vein thrombosis
S43. TX critical limb ischemia
S42. TX critical limb ischaemia
S41. TX claudication
S40. TX chronic limb ischemia
S39. TX chronic limb ischaemia
S38. TX arterial stenosis
S37. TX ankle brachial index
S36. TX abdominal aortic aneurysm
S35. TX abdominal aneurysm*
S34. TX AAA
S33. TX ((vein* or venous*) n (insufficien* or incomp*))
S32. TX ((varico* or reticular or thread or spider) n2 (vein* or venous)).
S31. (MH "Ulnar Artery/SU")
S30. (MH "Tibial Arteries/SU")
S29. (MH "Subclavian Vein/SU")
S28. (MH "Subclavian Artery/SU")
S27. (MH "Saphenous Vein/SU")
S26. (MH "Radial Artery/SU")
S25. (MH "Popliteal Vein/SU")
S24. (MH "Popliteal Artery/SU")
S23. (MH "Iliac Vein/SU")
S22. (MH "Iliac Artery/SU")
S21. (MH "Femoral Vein/SU")
S20. (MH "Femoral Artery/SU")
S19. (MH "Aorta, Thoracic/SU")
S18. (MH "Brachial Artery/SU")
S17. (MH "Axillary Vein/SU")
S16. (MH "Axillary Artery/SU")
S15. (MH "Aorta/SU")
S14. (MH "Venous Thrombosis+")
S13. (MH "Venous Thromboembolism")
S12. (MH "Venous Insufficiency+")
S11. (MH "Vascular Patency")
S10. (MH "Varicose Veins+")
S9. (MH "Upper Extremity Deep Vein Thrombosis")
S8. (MH "Thrombophlebitis+")
S7. (MH "Thromboembolism+")
S6. (MH "Telangiectasis+")
S5. (MH "Pulmonary Embolism")
S4. (MH "Peripheral Vascular Diseases+")
S3. (MH "Intermittent Claudication")
S2. (MH "Arterial Occlusive Diseases+")
S1. (MH "Aortic Aneurysm+")

ClinicalTrials.gov

Aortic Aneurysm OR Intermittent Claudication OR Peripheral Vascular Diseases OR Deep Vein Thrombosis OR Thromboembolism OR Venous Thromboembolism OR Venous Thrombosis OR Arterial Occlusive Diseases OR Pulmonary Embolism OR Venous Insufficiency

WHO’s ICTRP meta-registry

CENTRAL (via the Cochrane Library)

"Aortic Aneurysm" OR "Intermittent Claudication" OR "Peripheral Vascular Disease*" OR "Deep Vein Thrombosis" OR Thromboembolism OR "Venous Thromboembolism" OR "Venous Thrombosis" OR "Arterial Occlusive Diseases" OR "Pulmonary Embolism" OR "Venous Insufficiency"