PAD of lower limbs - Intermittent claudication - Chronic limb ischaemia

 Diagnosis and DTA reviews

Ankle brachial index for the diagnosis of lower limb peripheral arterial disease

Duplex ultrasound for detection of arterial re-stenosis after peripheral bypass grafting (protocol)

Positron emission tomography (PET) for the detection of vascular graft infections (protocol)

Screening for peripheral arterial disease

Toe-brachial index for the diagnosis of peripheral arterial disease (title)

 

Exercise and lifestyle (behaviour) modifications

Disease management interventions for improving self-management in lower-limb peripheral arterial disease (protocol)

Endovascular revascularisation versus conservative management for intermittent claudication

Exercise for intermittent claudication

Exercise programmes for intermittent claudication: an overview of Cochrane reviews (title)

Modes of exercise training for intermittent claudication

Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication

 

Medical (systemic) treatment

Anticoagulants (heparin, low molecular weight heparin and oral anticoagulants) for intermittent claudication

Antiplatelet agents for intermittent claudication

Beta blockers for peripheral arterial disease

Buflomedil for intermittent claudication

Chelation therapy for atherosclerotic cardiovascular disease

Cilostazol for intermittent claudication

Garlic for peripheral arterial occlusive disease (stable)

Ginkgo biloba for intermittent claudication

Homocysteine lowering interventions for peripheral arterial disease and bypass grafts

Intravenous naftidrofuryl for critical limb ischaemia (stable)

Lipid-lowering for peripheral arterial disease of the lower limb

Naftidrofuryl for intermittent claudication

Omega-3 fatty acids for intermittent claudication

Padma 28 for intermittent claudication (stable)

Pentoxifylline for critical limb ischaemia (protocol)

Pentoxifylline for intermittent claudication

Pharmacological treatment for Buerger's disease

Pharmacological interventions for intermittent claudication: an overview of Cochrane reviews (title)

Propionyl-L-Carnitine for intermittent claudication (protocol)

Prostanoids for critical limb ischaemia

Prostanoids for intermittent claudication

Sarpogrelate for peripheral arterial disease (protocol)

Sulodexide for treatment of peripheral vascular disease of the lower limbs (title)

Steroid sex hormones for lower limb atherosclerosis (stable)

Treatment of hypertension in peripheral arterial disease

Vitamin E for intermittent claudication

 

Angioplasty/stenting

Angioplasty and stenting for peripheral arterial disease of the lower limbs: an overview of Cochrane reviews (protocol)

Angioplasty (versus non surgical management) for intermittent claudication

Endovascular stents for intermittent claudication 

Endovascular versus open repair of asymptomatic popliteal artery aneurysm

Endovascular versus open surgery for atherosclerotic lesions of the Common Femoral Artery (CFA) (title)

Operative technique for the treatment of popliteal artery aneurysms (protocol)

1. Angioplasty versus stenting

Angioplasty versus bare metal stenting for superficial femoral artery lesions

Angioplasty versus stenting for iliac artery lesions

Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia

2. Comparison of different stent types and angioplasty techniques

Cryoplasty for peripheral arterial disease

Drug eluting balloon angioplasty versus uncoated balloon angioplasty for peripheral arterial disease of the lower limbs

Drug eluting balloon angioplasty versus uncoated balloon angioplasty for the treatment of in-stent restenosis of the femoropopliteal arteries (protocol)

Endoluminal stents for iliac and infrainguinal arterial disease (protocol) 

Femoral versus retrograde distal access for below the knee angioplasty (title)

Intravascular brachytherapy for peripheral vascular disease

Subintimal angioplasty for chronic lower limb arterial occlusion

3. Prevention of restenosis – systemic treatments

Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment

 

Local non-surgical, non-angioplasty interventions

1. Local thrombolysis

Fibrinolytic agents for peripheral arterial occlusion

Infusion techniques for peripheral arterial thrombolysis

Percutaneous thrombectomy for initial management of acute limb ischaemia (title)

Surgery versus thrombolysis for initial management of acute limb ischaemia

2. Other

Autologous cells derived from different sources and administered using different regimens for ’no-option’ critical lower limb ischaemia patients

Dressings and topical agents for arterial leg ulcers

Gene therapy for peripheral arterial disease

Growth factors for angiogenesis in peripheral vascular disease

Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia

Lumbar sympathectomy techniques for critical lower limb ischaemia due to non-reconstructable peripheral arterial disease

Lumbar sympathectomy versus prostanoids for critical limb ischaemia due to non-reconstructable peripheral arterial disease (protocol)

Intermittent pneumatic compression for critical limb ischaemia (protocol)

Shockwave therapy for peripheral arterial disease (title)

Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia (stable)

Stem cell therapy for treatment of thromboangiitis obliterans (Buerger's disease)
 

Surgical interventions

Prehabilitation prior to lower limb surgery in adults with peripheral arterial disease (title)

1. Bypass

Anatomical iliofemoral bypass versus extra-anatomical crossover grafting for symptomatic unilateral iliac disease  (protocol)

Bypass surgery for chronic lower limb ischaemia (update)

Distal venous arterialisation (DVA) for the salvage of critically ischemic lower limbs (title)

Graft type for femoro-popliteal bypass surgery

Interposition vein cuff for infragenicular prosthetic bypass graft

Prevention of infection in arterial reconstruction

2. Atherectomy

Atherectomy for peripheral arterial disease

3. Prevention of bypass graft thrombosis – systemic treatment

Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery

Antithrombotic agents for preventing thrombosis after infrainguinal arterial bypass surgery

 

Lower limb amputation

Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral amputation

Type of incision for below knee amputation