PAD of lower limbs - Intermittent claudication - Chronic limb ischaemia

Diagnosis and Diagnostic Test Accuracy (DTA) reviews
Intervention reviews 
- Exercise and lifestyle (behaviour) modifications
- Medical (systemic) treatment
-- for PAD
-- for intermittent claudication
-- for critical limb ischaemia
-- other
- Angioplasty/stenting 
-- Angioplasty versus stenting
-- Comparison of different stent types and angioplasty techniques 
- Prevention of restenosis (systemic treatment) 
- Local non-surgical, non-angioplasty interventions 
-- Local thrombolysis/
thrombectomy 
-- Other
- Surgical interventions
-- Bypass 
-- Atherectomy 
- Prevention of bypass graft thrombosis (systemic treatment) 
- Limb amputation
-
Thromboangiitis obliterans (Buerger's disease)

Diagnosis and Diagnostic Test Accuracy (DTA) reviews

Ankle brachial index for the diagnosis of lower limb peripheral arterial disease

Duplex ultrasound for detection of arterial re-stenosis after peripheral bypass grafting (protocol)

Positron emission tomography (PET) for the detection of vascular graft infections (protocol)

Screening for peripheral arterial disease

Toe-brachial index for the diagnosis of peripheral arterial disease (title)


Intervention reviews

Exercise and lifestyle (behaviour) modifications

Disease management interventions for improving self-management in lower-limb peripheral arterial disease (protocol)

Effects of additional exercise therapy after a vascular intervention for patients with intermittent claudication (title)

Endovascular revascularisation versus conservative management for intermittent claudication

Exercise for intermittent claudication

Mobile health technologies to improve walking distance in patients with intermittent claudication (title) 

Modes of exercise training for intermittent claudication

Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication

 

Medical (systemic treatment)

- for PAD

Beta blockers for peripheral arterial disease

Garlic for peripheral arterial occlusive disease (stable)

Homocysteine lowering interventions for peripheral arterial disease and bypass grafts (stable)

Lipid-lowering for peripheral arterial disease of the lower limb

Sarpogrelate for peripheral arterial disease (protocol)

Steroid sex hormones for lower limb atherosclerosis (stable)

Treatment of hypertension in peripheral arterial disease

- for intermittent claudication

Anticoagulants (heparin, low molecular weight heparin and oral anticoagulants) for intermittent claudication

Buflomedil for intermittent claudication

Cilostazol for intermittent claudication

Ginkgo biloba for intermittent claudication (stable)

Naftidrofuryl for intermittent claudication

Omega-3 fatty acids for intermittent claudication

Padma 28 for intermittent claudication (stable)

Pentoxifylline for intermittent claudication

Propionyl-L-Carnitine for intermittent claudication (protocol)

Pentoxifylline for critical limb ischaemia (protocol)

Prostanoids for intermittent claudication

Vitamin E for intermittent claudication

- for critical limb ischaemia

Intravenous naftidrofuryl for critical limb ischaemia (stable)

Prostanoids for critical limb ischaemia

- other

Chelation therapy for atherosclerotic cardiovascular disease

Angioplasty/stenting

Angioplasty and stenting for peripheral arterial disease of the lower limbs: an overview of Cochrane reviews (protocol)

Angioplasty (versus non surgical management) for intermittent claudication

Endovascular stents for intermittent claudication 

Endovascular versus open repair of asymptomatic popliteal artery aneurysm

Endovascular versus open surgical endarterectomy for atherosclerotic lesions of the common femoral artery (CFA) (protocol)

Operative technique for the treatment of popliteal artery aneurysms (protocol)

Surgical versus endoluminal intervention for stenosis in infrainguinal vein grafts (title)

Angioplasty versus stenting

Angioplasty versus bare metal stenting for superficial femoral artery lesions

Angioplasty versus stenting for iliac artery lesions

Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia

Comparison of different stent types and angioplasty techniques

Cryoplasty for peripheral arterial disease

Drug eluting balloon angioplasty versus uncoated balloon angioplasty for peripheral arterial disease of the lower limbs

Drug eluting balloon angioplasty versus uncoated balloon angioplasty for the treatment of in-stent restenosis of the femoropopliteal arteries (protocol)

Endoluminal stents for iliac and infrainguinal arterial disease (protocol) 

Retrograde distal access versus femoral access for below the knee angioplasty (protocol)

Intravascular brachytherapy for peripheral vascular disease (stable)

Subintimal angioplasty for chronic lower limb arterial occlusion

Prevention of restenosis (systemic treatments)

Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment

Local non-surgical, non-angioplasty interventions

Local thrombolysis/thrombectomy

Fibrinolytic agents for peripheral arterial occlusion

Infusion techniques for peripheral arterial thrombolysis

Percutaneous thrombectomy for initial management of acute limb ischaemia (protocol)

Surgery versus thrombolysis for initial management of acute limb ischaemia

Other

Alternative non-invasive treatment therapies for for patients with intermittent claudication (title)

Autologous cells derived from different sources and administered using different regimens for ’no-option’ critical lower limb ischaemia patients

Dressings and topical agents for arterial leg ulcers

Duplex ultrasound for surveillance of lower limb revascularisation (title)

Extracorporeal shockwave therapy for peripheral arterial disease (protocol)

Gene therapy for peripheral arterial disease

Growth factors for angiogenesis in peripheral vascular disease

Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia

Lumbar sympathectomy techniques for critical lower limb ischaemia due to non-reconstructable peripheral arterial disease

Lumbar sympathectomy versus prostanoids for critical limb ischaemia due to non-reconstructable peripheral arterial disease (protocol)

Intermittent pneumatic compression for critical limb ischaemia (protocol)

Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia (stable) 

Surgical interventions

Prehabilitation prior to lower limb surgery in adults with peripheral arterial disease (protocol)

Bypass

Anatomical iliofemoral bypass versus extra-anatomical crossover grafting for symptomatic unilateral iliac disease  (protocol)

Bypass surgery for chronic lower limb ischaemia (update)

Distal venous arterialisation (DVA) for the salvage of critically ischemic lower limbs (title)

Graft type for femoro-popliteal bypass surgery

Interposition vein cuff for infragenicular prosthetic bypass graft

Prevention of infection in arterial reconstruction

Atherectomy

Atherectomy for peripheral arterial disease

Prevention of bypass graft thrombosis (systemic treatment)

Antiplatelet agents for preventing thrombosis after peripheral arterial bypass surgery

Antithrombotic agents for preventing thrombosis after infrainguinal arterial bypass surgery

Limb amputation

Interventions for motor rehabilitation in patients with dysvascular amputations (title)

Non-surgical interventions for preventing contralateral tissue loss and amputation in dysvascular patients with a primary major lower limb amputation (title)

Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral amputation

Through knee versus above knee for vascular and non-vascular amputations (title)

Type of incision for below knee amputation

Thromboangiitis obliterans (Buerger's disease)

Pharmacological treatment for Buerger's disease

Stem cell therapy for treatment of Thromboangiitis obliterans (Buerger's disease)